CCL7 Antikörper (Biotin)

Produktnummer ABIN453919

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CCL7 in EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CCL7 Antikörper (Biotin) (ABIN453919)

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCL7 Antikörper ist konjugiert mit Biotin

Applikation: Enzyme Immunoassay (EIA)

Klon: 113

Produktdetails anti-CCL7 Antikörper (Biotin)

Spezifität: Reactive with natural and recombinant human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Purified Recombinant Human Monocyte Chemotactic Protein-3 (MCP-3).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: This MCP3 antibody Biotin-conjugated can be used as a Tracer/Detection Antibodyin Sandwich ELISA applications for human MCP-3 detection in combination with a Captureantibody (Cat#DM2039)Suggested Capture Coating Dose: 3 μg/wellSubstrate: TMB
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0 ± 0.1, 0.1 % Proclin-300, 1 % Gelatin

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C. DO NOT FREEZE!

Details zu CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Andere Bezeichnung: MCP3 / CCL7

Hintergrund: Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78 % sequence homology with MCP-1 and 58 % sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7

Gen-ID: 6354

NCBI Accession: NP_006264

UniProt: P80098