This antibody reacts to Interleukin-16. IL16 antibody clone 323 exhibits no detectable cross-reacting with human albumin serum, Bovine albumin serum and other human cytokines or growth factors tested such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta 1, EGF, bFGF, GM-CSF, M-CSF, TNF-alpha.
IL16
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore with Double distillated water to adjust the final concentration to 1.00 mg/mL.
Buffer
0.01 M PBS, pH 7.2 without preservatives.
Konservierungsmittel
Without preservative
Handhabung
This product is photosensitive and should be protected from light
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody at 2 - 8 °C. DO NOT FREEZE!
Target
IL16
(Interleukin 16 (IL16))
Andere Bezeichnung
Interleukin-16 / IL16
Hintergrund
Interleukin-16 (IL16) is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor