SAA Antikörper (Biotin)

Produktnummer ABIN453894

Produktdetails anti-SAA Antikörper (Biotin)

Target: SAA (Serum Amyloid A (SAA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SAA Antikörper ist konjugiert mit Biotin

Applikation: Enzyme Immunoassay (EIA), ELISA (Detection)

Spezifität: This antibody reacts with natural and recombinant SAA. Does not show any cross-reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, TGF-beta and EGF.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Highly purified recombinant Human SAA (MW: 12 kDa)

Klon: 607

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0±0.1, 0.1 % Proclin-300, 1 % Gelatin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.

Details zu SAA

Target: SAA (Serum Amyloid A (SAA))

Andere Bezeichnung: Serum Amyloid A Protein (SAA) (SAA Produkte)

Synonyme: PIG4 antikoerper, SAA antikoerper, SAA2 antikoerper, TP53I4 antikoerper, zgc:103580 antikoerper, saa antikoerper, SAA1 antikoerper, Saa-1 antikoerper, Saa2 antikoerper, serum amyloid A1 antikoerper, serum amyloid A antikoerper, serum amyloid A protein antikoerper, serum amyloid A-3 antikoerper, HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 antikoerper, serum amyloid A2 antikoerper, serum amyloid A 1 antikoerper, SAA1 antikoerper, saa antikoerper, LOC476879 antikoerper, SAA antikoerper, SAA3 antikoerper, HPS5 antikoerper, SAA2 antikoerper, Saa1 antikoerper, LOC100270725 antikoerper

Hintergrund: The serum amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.Synonyms: SAA1, SAA2

Gen-ID: 6288

NCBI Accession: NP_000322

UniProt: P02735