PRELP Antikörper (C-Term)
Kurzübersicht für PRELP Antikörper (C-Term) (ABIN453297)
Target
Alle PRELP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody reacts to PRELP.
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Aufreinigung
- Saturated Ammonium Sulfate (SAS) precipitation
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Immunogen
- KLH conjugated synthetic peptide selected from the C-terminal region of human PRELP
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Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
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Andere Bezeichnung
- Prolargin / PRELP
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Hintergrund
- PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.Synonyms: Proline-arginine-rich end leucine-rich repeat protein, SLRR2A
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Gen-ID
- 5549
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NCBI Accession
- NP_002716
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UniProt
- P51888
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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