HFE Antikörper (Middle Region)
Kurzübersicht für HFE Antikörper (Middle Region) (ABIN453091)
Target
Alle HFE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Spezifität
- This antibody detects HFE at Center.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogen
- KLH conjugated synthetic peptide selected from the Center region of human HFE
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Applikationshinweise
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Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- HFE (Hemochromatosis (HFE))
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Andere Bezeichnung
- HFE / HLAH
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Hintergrund
- HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.Synonyms: Hereditary hemochromatosis protein
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Molekulargewicht
- 40108 Da
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Gen-ID
- 3077
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NCBI Accession
- NP_000401
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UniProt
- Q30201
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Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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