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FKBP1B Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FKBP1B in WB und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN453013

Kurzübersicht für FKBP1B Antikörper (N-Term) (ABIN453013)

Target

Alle FKBP1B Antikörper anzeigen
FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Reaktivität

  • 27
  • 23
  • 18
  • 5
Human, Maus

Wirt

  • 48
  • 2
Kaninchen

Klonalität

  • 49
  • 1
Polyklonal

Konjugat

  • 23
  • 7
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FKBP1B Antikörper ist unkonjugiert

Applikation

  • 30
  • 20
  • 15
  • 13
  • 13
  • 11
  • 10
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    N-Term

    Spezifität

    This antibody detects FKBP1B at N-term.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, mouse

    Aufreinigung

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    Immunogen

    KLH conjugated synthetic peptide selected from the N-terminal region of human FKBP1B
  • Applikationshinweise

    Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target

    FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

    Andere Bezeichnung

    FKBP1B / FKBP9

    Hintergrund

    FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.Synonyms: FK506-binding protein 1B, FKBP12.6, FKBP1L, Immunophilin FKBP12.6, OTK4, PPIase FKBP1B, Peptidyl-prolyl cis-trans isomerase FKBP1B, Rotamase, h-FKBP-12

    Molekulargewicht

    11783 Da

    Gen-ID

    2281

    NCBI Accession

    NP_004107

    UniProt

    P68106

    Pathways

    Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity
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