TNK2 Antikörper (N-Term)

Produktnummer ABIN452711

Produktdetails anti-TNK2 Antikörper

Target: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects TNK2 / ACK1 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human ACK1

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TNK2

Target: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Andere Bezeichnung: TNK2 / ACK1 (TNK2 Produkte)

Synonyme: ACK antikoerper, ACK-1 antikoerper, ACK1 antikoerper, p21cdc42Hs antikoerper, AW552477 antikoerper, Ack antikoerper, Cdgip antikoerper, Pyk1 antikoerper, ack1 antikoerper, ackb antikoerper, tnk2 antikoerper, tnk2b antikoerper, wu:fj16g04 antikoerper, zgc:154019 antikoerper, tyrosine kinase non receptor 2 antikoerper, tyrosine kinase, non-receptor, 2 antikoerper, tyrosine kinase, non-receptor, 1 antikoerper, TNK2 antikoerper, Tnk2 antikoerper, tnk1 antikoerper

Hintergrund: ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1

Molekulargewicht: 114327 Da

Gen-ID: 10188

NCBI Accession: NP_001010938

UniProt: Q07912