TNK2 Antikörper (Middle Region)
Kurzübersicht für TNK2 Antikörper (Middle Region) (ABIN452710)
Target
Alle TNK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Spezifität
- This antibody detects TNK2 / ACK1 at Center.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogen
- KLH conjugated synthetic peptide selected from the Center region of human ACK1
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Applikationshinweise
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ELISA: 1: 1,000. Western blot: 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
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Andere Bezeichnung
- TNK2 / ACK1
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Hintergrund
- ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1
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Molekulargewicht
- 114327 Da
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Gen-ID
- 10188
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NCBI Accession
- NP_001010938
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UniProt
- Q07912
Target
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