TFB1M Antikörper (C-Term)

Produktnummer ABIN452674

Dieser Ziege Polyklonal Antikörper detektiert spezifisch TFB1M in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human und Hund.

Kurzübersicht für TFB1M Antikörper (C-Term) (ABIN452674)

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Reaktivität: Human, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TFB1M Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TFB1M Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-ELKRRKSKNEEKE, from the C-Terminus of Human TFB1M (NP_057104.2).

Anwendungsinformationen

Applikationshinweise: TFB1M antibody can be used for: Peptide ELISA: Detection limit dilution 1/64000. Western blot: 0.3-1 μg/mL. Approx 38 kDa band observed in lysates of cell line A431(calculated MW of 39.8 kDa according to NP_057104.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Expected from sequence similarity: Canine (Dog).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu TFB1M

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Andere Bezeichnung: TFB1M

Hintergrund: TFB1M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity.Synonyms: CGI-75, Dimethyladenosine transferase 1 mitochondrial, Mitochondrial 12S rRNA dimethylase 1, Mitochondrial transcription factor B1, N'-adenosyl(rRNA) dimethyltransferase 1, S-adenosylmethionine-6-N', mtTFB1

Gen-ID: 51106

NCBI Accession: NP_057104

UniProt: Q8WVM0