SAA Antikörper

Produktnummer ABIN452611

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SAA in EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SAA Antikörper (ABIN452611)

Target: SAA (Serum Amyloid A (SAA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SAA Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: 132

Produktdetails anti-SAA Antikörper

Spezifität: Reacts with natural and recombinant Human SAA. Does not show any cross-reaction with other Human Cytokines or Growth Factors tested such as IL1 beta, IL-8, MCAF, TGF beta and EGF.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: SAA1, SAA2

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Highly purified recombinant Human SAA. Remarks: Molecular Weight: 12 kDa

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: Use of this SSA antibody at a concentration of 0.1-0.5 μg will allowvisualization of 100 ng/lane of recombinant Human SAA.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu SAA

Target: SAA (Serum Amyloid A (SAA))

Andere Bezeichnung: Serum Amyloid A Protein (SAA)

Hintergrund: The Serum Amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.Synonyms: SAA1, SAA2

Gen-ID: 6288

UniProt: P02735