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CD41, CD61 Antikörper

Reaktivität: Human EIA, WB Wirt: Maus Monoclonal 8 unconjugated
Produktnummer ABIN452603
  • Target Alle CD41, CD61 Antikörper anzeigen
    CD41, CD61 (CD41,CD61)
    Reaktivität
    • 18
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 26
    Maus
    Klonalität
    • 26
    Monoklonal
    Konjugat
    • 10
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser CD41, CD61 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Enzyme Immunoassay (EIA), Western Blotting (WB)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Produktmerkmale
    Synonyms: Platelet Membrane GPIIb-IIIa Complex, CD41b, CD61, GP3A, GPIIIa, GPIIIb, GTA, HPA3,Integrin alpha 2b, Integrin beta 3
    Aufreinigung
    Affinity Chromatography on Protein G.
    Immunogen
    10e9 Human platelets suspension. The supernatant fluid from positive clones was screened by ELISA coated with washedplatelets.
    Klon
    8
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD41, CD61 Primärantikörper
  • Applikationshinweise
    This GPIIb/IIIa antibody is Suitable for use in ELISA and Western Blot. Use of this Monoclonal antibody at a concentration of 10-20 μg/mL (culture supernatants)will allow visualization of NP 40 solubilized human normal platelets. The titer of purified ascites was determined by ELISA coated with 100 μL of 1x10e8 washedplatelets.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
    Buffer
    0.01 M PBS, pH 7.2 without preservatives.
    Konservierungsmittel
    Without preservative
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    CD41, CD61 (CD41,CD61)
    Abstract
    CD41, CD61 Produkte
    Hintergrund
    The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
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