Der Maus Monoklonal Anti-Coagulation Factor IX-Antikörper wurde für EIA validiert. Er ist geeignet, Coagulation Factor IX in Proben von Human zu detektieren.
Produktnummer ABIN452591
Kurzübersicht für Coagulation Factor IX Antikörper (ABIN452591)
F9
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore with Double distillated water to a final concentration of 1.0 mg/mL.
Buffer
0.01 M PBS, pH 7.2 without preservatives.
Konservierungsmittel
Without preservative
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
Coagulation Factor IX (F9)
Hintergrund
Factor IX circulates in the blood as an inactive zymogen at the normal concentration of approximately 3 μg/mL. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca2+ ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X linked disorder, also called hemophilia B or Christmas disease. The disease affects approximately 1 in 50,000 of the population (almost exclusively males).Synonyms: Christmas factor, PTC, Plasma thromboplastin component