CRP Antikörper

Produktnummer ABIN452590

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CRP in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CRP Antikörper (ABIN452590)

Target: CRP (C-Reactive Protein (CRP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CRP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: S5G1

Produktdetails anti-CRP Antikörper

Spezifität: Reactive with Human CRP in Immunoblot and ELISA

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: PTX1, C Reactive Protein, Pentraxin-related

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Purified CRP from human pleural fluid.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISAImmunoblotting (Western).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CRP

Target: CRP (C-Reactive Protein (CRP))

Hintergrund: C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.Synonyms: C Reactive Protein, PTX1, Pentraxin-related

Gen-ID: 1401

UniProt: P02741

Pathways: Carbohydrate Homeostasis