SYT1 Antikörper (Ser309)
Kurzübersicht für SYT1 Antikörper (Ser309) (ABIN401634)
Target
Alle SYT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Ser309
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Spezifität
- Synaptotagmin Antibody detects endogenous levels of total Synaptotagmin protein.
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Aufreinigung
- Affinity chromatography
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Immunogen
- Synthesized non-phosphopeptide derived from human Synaptotagmin around the phosphorylation site of serine 309 (G-L-SP-D-P)
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anti-Synaptotagmin I (SYT1) (AA 1-422) antibody
SYT1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 136-422) antibodySYT1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 Reaktivität: Human, Ratte, Maus WB, IHC, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3A5 unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1A6 unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-19), (Intravesicular), (N-Term) antibodySYT1 Reaktivität: Ratte WB, IHC Wirt: Meerschweinchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 Reaktivität: Human, Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (Internal Region) antibodyVerified SYT1 Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-423) antibodySYT1 Reaktivität: Human WB, IHC, ELISA, IHC (p) Wirt: Maus Monoclonal 1A6 unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Huhn, Hund WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Immunofluorescence: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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- SYT1 (Synaptotagmin I (SYT1))
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Andere Bezeichnung
- Synaptotagmin-1
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Hintergrund
- Synaptotagmin 1 is a 60 kDa member of the synaptotagmin family, expressed in membranes of synaptic vesicles in rostral, phylogenetically younger brain regions and in some endocrine tissues. Ca2+ is bound by synaptogamin whose C2 domains then bind phospholipids, trafficking vesicles to the synaptic membrane and exocytosis. This results in fast synchronous neurotransmitter release. Synaptotagmin also binds neurexins, syntaxin and AP2 independently of Ca2+ binding. Phosphorylation of synaptotagmin by protein kinases is thought to modulate its activity.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
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Gen-ID
- 6857
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NCBI Accession
- NP_001129277
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UniProt
- P21579
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Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Target
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