The antibody detects endogenous level of Synaptotagmin only when phosphorylated at Serine 309.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, Mouse, Rat.
Aufreinigung
Affinity Chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Immunogen
Peptide sequence around phosphorylation site of Serine 309 (G-L-S(p)-D-P) derived from Human.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide, 50 % Glycerol
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
SYT1
(Synaptotagmin I (SYT1))
Andere Bezeichnung
Synaptotagmin-1
Hintergrund
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65