Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Tyrosine Hydroxylase Antikörper (pSer19)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Tyrosine Hydroxylase in IF. Er zeigt eine Reaktivität gegenüber Ratte.
Produktnummer ABIN401584

Kurzübersicht für Tyrosine Hydroxylase Antikörper (pSer19) (ABIN401584)

Target

Alle Tyrosine Hydroxylase (TH) Antikörper anzeigen
Tyrosine Hydroxylase (TH)

Reaktivität

  • 126
  • 122
  • 101
  • 11
  • 11
  • 9
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 121
  • 39
  • 7
  • 6
  • 2
Kaninchen

Klonalität

  • 125
  • 48
  • 1
Polyklonal

Konjugat

  • 123
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Tyrosine Hydroxylase Antikörper ist unkonjugiert

Applikation

  • 127
  • 93
  • 45
  • 34
  • 32
  • 27
  • 22
  • 17
  • 14
  • 13
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • Bindungsspezifität

    • 20
    • 15
    • 14
    • 12
    • 12
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer19

    Spezifität

    Antibody AP09482PU detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at Serine 19.

    Aufreinigung

    Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    Immunogen

    The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Serine19 (A-V-Sp-E-Q).
  • Applikationshinweise

    Immunofluorescence: 1/100approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store the antibody (in aliquots) at-20 °C.
  • Target

    Tyrosine Hydroxylase (TH)

    Andere Bezeichnung

    Tyrosine 3-Monooxygenase (TH)

    Hintergrund

    Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's diseaseSynonyms: TYH, Tyrosine 3-hydroxylase

    Gen-ID

    7054

    NCBI Accession

    NP_000351

    UniProt

    P07101

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Sie sind hier:
Chat with us!