RSL1D1 Antikörper (Internal Region)

Produktnummer ABIN401398

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RSL1D1 in WB, IF, IP und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RSL1D1 Antikörper (Internal Region) (ABIN401398)

Target: RSL1D1 (Ribosomal L1 Domain Containing 1 (RSL1D1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RSL1D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Produktdetails anti-RSL1D1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody is specific for PBK1 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide corresponding to an internal sequence of human PBK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/2,500 - 1/10,000. WESTWestern Blot: 1/500 - 1/2,000. Immunoprecipitation: 1/100. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.1 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu RSL1D1

Target: RSL1D1 (Ribosomal L1 Domain Containing 1 (RSL1D1))

Andere Bezeichnung: RSL1D1

Hintergrund: PBK1 protein (also known as Ribosomal L1 domain-containing protein 1, cellular senescence-inhibited gene protein, and CATX-11) was isolated from highly invasive first trimester trophoblast cells and has been proposed to regulate their naturally occurring invasive behavior (Huch et al., 1998). PBK1 was also found to be over-expressed in non-small-cell lung cancer (NSCLC) cells (Petroziello et al., 2004). A recent study suggests that PBK1 may up-regulate the urokinase-type plasminogen activator (uPA) gene, which plays an important role in cellular matrix degradation and activation of other protease systems involved in cell invasion (Tong et al., 2005). PBK1 shows a nuclear and nucleolar localization.Synonyms: CATX-11, CSIG, Cellular senescence-inhibited gene protein, PBK1, Ribosomal L1 domain-containing protein 1

Gen-ID: 26156

NCBI Accession: NP_056474

UniProt: O76021