Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CASZ1 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh) und Schimpanse.
ELISA: 1/25,000 - 1/100,000. Western blot: 1/1,000 - 1/3,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.3 mg/mL (by UV absorbance at 280 nm)
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Target
CASZ1
(Castor Zinc Finger 1 (CASZ1))
Andere Bezeichnung
CASZ1
Hintergrund
HCas5 (Castor) is the human homolog of a Drosophila gene that regulates neurogenesis. In human neuroblastoma tumors where a loss of heterozygosity of CASZ1 is noted, hCas functions to suppress the tumorigenicity of cells. hCas5 is a developmentally regulated transcription factor found in neural and muscle cells. hCas5 is a Zn finger transcription factor that is predominantly found in the nucleus. This antibody is designed to facilitate the functional study of this protein and its role in developmental regulation and expression in human tumor tissues.Synonyms: CST, Castor-related protein, Putative survival-related protein, SRG, ZNF693, Zinc finger protein 693, Zinc finger protein castor homolog 1