CTCFL Antikörper (AA 9-26)

Produktnummer ABIN401325

Der Kaninchen Polyklonal anti-CTCFL Antikörper (ABIN401325) detektiert spezifisch CTCFL in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Schimpanse.

Kurzübersicht für CTCFL Antikörper (AA 9-26) (ABIN401325)

Target: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Reaktivität: Human, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTCFL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CTCFL Antikörper

Bindungsspezifität: AA 9-26

Spezifität: This antibody is directed against the BORIS protein.

Kreuzreaktivität (Details): Species reactivity (expected):Chimpanzee.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding aa 9-26 of human BORIS protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.28 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CTCFL

Target: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Andere Bezeichnung: CTCFL / BORIS

Hintergrund: BORIS (Brother of the Regulator of Imprinted Sites) also known as CCCTC-binding factor-like protein, is normally only expressed in the testis and expressed in a mutually exclusive manner with CTCF during male germ cell development. However, previous studies have shown that BORIS is abnormally activated in a wide range of human cancers. Expression of BORIS in normally BORIS-negative cells promotes cell growth that may lead to transformation. BORIS maps to the cancer-associated amplification region thought to contain an oncogene or dominant-immortalizing gene. BORIS is a candidate protein for the epigenetic reprogramming factor acting in the male germ line. BORIS is found in both the nucleus and cytoplasm.Synonyms: Brother of the regulator of imprinted sites, CCCTC-binding factor, CT27, CTCF paralog, CTCF-T, CTCF-like protein, Cancer/testis antigen 27, Transcriptional repressor CTCFL, Zinc finger protein CTCF-T

Gen-ID: 140690

NCBI Accession: NP_542185

UniProt: Q8NI51