SLIT1 Antikörper (AA 487-504)

Produktnummer ABIN401297

Der Kaninchen Polyklonal anti-SLIT1 Antikörper wird verwendet zum Nachweis von SLIT1 in Proben von Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für SLIT1 Antikörper (AA 487-504) (ABIN401297)

Target: SLIT1 (Slit Homolog 1 (SLIT1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLIT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SLIT1 Antikörper

Bindungsspezifität: AA 487-504

Spezifität: This antibody is directed against SLIT-1 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Human, Chicken Frog.
Species reactivity (tested):Mouse.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding aa 487-504 of mouse SLIT-1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10,000 - 1/50,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.2 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu SLIT1

Target: SLIT1 (Slit Homolog 1 (SLIT1))

Andere Bezeichnung: SLIT1

Hintergrund: SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.Synonyms: KIAA0813, MEGF4, Multiple epidermal growth factor-like domains protein 4, SLIL1, SLIT-1, Slit homolog 1 protein

Gen-ID: 20562

NCBI Accession: NP_056563

UniProt: Q80TR4

Pathways: Regulation of Cell Size