FBXW11 Antikörper (N-Term)

Produktnummer ABIN401257

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBXW11 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus, Hund, Rind (Kuh), Pferd, Huhn und Schimpanse.

Kurzübersicht für FBXW11 Antikörper (N-Term) (ABIN401257)

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Reaktivität: Human, Maus, Hund, Rind (Kuh), Pferd, Huhn, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FBXW11 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts with betaTrCP2 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Canine, Bovine, Chimpanzee, Chicken, Horse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding to a region near the N-terminal of human betaTrCP2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10,000 - 1/100,000. Western Blot: 1/200 - 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu FBXW11

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Andere Bezeichnung: FBW1B

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.Synonyms: BTRCP2, F-box and WD repeats protein beta-TrCP2, F-box/WD repeat-containing protein 11, F-box/WD repeat-containing protein 1B, FBXW11, FBXW1B, HOS, Homologous to Slimb protein, KIAA0696, beta-TrCP2

Gen-ID: 23291

NCBI Accession: NP_036432

UniProt: Q9UKB1