FBXW11 Antikörper (N-Term)

Produktnummer ABIN401257

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch FBXW11 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus, Hund, Rind (Kuh), Pferd, Huhn und Schimpanse.

Kurzübersicht für FBXW11 Antikörper (N-Term) (ABIN401257)

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Reaktivität: Human, Maus, Hund, Rind (Kuh), Pferd, Huhn, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FBXW11 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts with betaTrCP2 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Canine, Bovine, Chimpanzee, Chicken, Horse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding to a region near the N-terminal of human betaTrCP2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10,000 - 1/100,000. Western Blot: 1/200 - 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu FBXW11

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Andere Bezeichnung: FBW1B

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.Synonyms: BTRCP2, F-box and WD repeats protein beta-TrCP2, F-box/WD repeat-containing protein 11, F-box/WD repeat-containing protein 1B, FBXW11, FBXW1B, HOS, Homologous to Slimb protein, KIAA0696, beta-TrCP2

Gen-ID: 23291

NCBI Accession: NP_036432

UniProt: Q9UKB1