CCL20 Antikörper

Produktnummer ABIN401107

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CCL20 in WB, IHC, ELISA, Neut und RIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CCL20 Antikörper (ABIN401107)

Target: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Neutralization (Neut), Radioimmunoassay (RIA)

Produktdetails anti-CCL20 Antikörper

Spezifität: This antibody reacts to MIP3 alpha.

Aufreinigung: Ig Fraction

Immunogen: Full length recombinant human MIP-3a protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot. Reactivity is also expected in neutralizations, radioimmunoassay andimmunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.1 mL of deionized water (or equivalent).

Konzentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CCL20

Target: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Andere Bezeichnung: MIP3 alpha / CCL20

Hintergrund: MIP-3a (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3a inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3a also possesses antibacterial activity against E.coli and S.aureus. MIP-3a is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.Synonyms: Beta chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CCL20, DC marker, Dendritic Cell Marker, Exodus-1, LARC, Liver and activation-regulated chemokine, MIP-3 alpha, MIP3A, Macrophage inflammatory protein 3 alpha, SCYA20, Small-inducible cytokine A20

Gen-ID: 6364

NCBI Accession: NP_001123518

UniProt: P78556

Pathways: Phosphorylierungen bei SARS-CoV-2 Infektion