IL-33 Antikörper

Produktnummer ABIN401105

Der Kaninchen Polyklonal anti-IL-33 Antikörper wird verwendet zum Nachweis von IL-33 in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für IL-33 Antikörper (ABIN401105)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-IL-33 Antikörper

Spezifität: This antibody reacts to Interleukin-33.

Aufreinigung: Ig Fraction

Immunogen: Full length recombinant human IL-33 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/20,000 - 1/100,000. Western Blot: 1/500 - 1/2,000. Neutralization: 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.1 mL of deionized water (or equivalent).

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu IL-33

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Andere Bezeichnung: Interleukin-33 (IL33)

Hintergrund: IL-33 (also known as Interleukin-33, Interleukin-1 family member 11, IL-1F11, nuclear factor from high endothelial venules and NF-HEV) is a cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL-33 induces T helper type 2-associated cytokines. IL-33 is a secreted cytokine that is expressed at high levels in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes and is almost undetectable in placenta. The 31 kDa precursor is proteolytically converted to an 18 kDa mature form by CASP1.Synonyms: C9orf26, IL-1F11, IL-33, IL1F11, Interleukin-1 family member 11, NF-HEV, NFHEV, Nuclear factor from high endothelial venules

Gen-ID: 90865

NCBI Accession: NP_254274

UniProt: O95760

Pathways: Production of Molecular Mediator of Immune Response