ENPP3 Antikörper (PE)
Kurzübersicht für ENPP3 Antikörper (PE) (ABIN400883)
Target
Alle ENPP3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The antibody NP4D6 reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
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Produktmerkmale
- Synonyms: E-NPP 3, PDNP3, Phosphodiesterase I beta, PD-I beta, Ectonucleotide pyrophosphatase /phosphodiesterase family member 3, Phosphodiesterase I/nucleotide pyrophosphatase 3
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Aufreinigung
- Size-Exclusion Chromatography
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Immunogen
- HEK-293 cells transfected with human CD203c
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Isotyp
- IgG1
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Applikationshinweise
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Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 mLof whole bloodor 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, 15 mM Sodium Azide, 0.2 % high-grade protease free BSA as a stabilizing agent
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Store at 2-8 °C. Do not freeze. This antibody is photosensitive and should be protected fromlight.
Shelf life: One year from despatch. -
Haltbarkeit
- 12 months
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- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
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Andere Bezeichnung
- CD203c / ENPP3
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Hintergrund
- CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.Synonyms: E-NPP 3, Ectonucleotide pyrophosphatase / phosphodiesterase family member 3, PD-I beta, PDNP3, Phosphodiesterase I beta, Phosphodiesterase I/nucleotide pyrophosphatase 3
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Gen-ID
- 5169
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UniProt
- O14638
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Pathways
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
Target
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