This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This PTP gamma antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-782 amino acids from the Central region of human PTP gamma.
HPTPG antikoerper, PTPG antikoerper, R-PTP-GAMMA antikoerper, RPTPG antikoerper, 5430405N12Rik antikoerper, AW046354 antikoerper, AW549872 antikoerper, RPTPgamma antikoerper, Ptpg antikoerper, protein tyrosine phosphatase, receptor type G antikoerper, protein tyrosine phosphatase, receptor type, G antikoerper, PTPRG antikoerper, Ptprg antikoerper
Hintergrund
PTPgamma is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. The gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.