EPS8 Antikörper (N-Term)

Produktnummer ABIN392773

Produktdetails anti-EPS8 Antikörper

Target: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Bindungsspezifität: AA 9-39, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPS8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EPS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human EPS8.

Klon: RB4003

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:2000. WB: 1:2000. WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-EPS8 Antikörper (ABIN392773)

Nasr, Mukhopadhyay, Zhang, Katzenstein: "Immunohistochemical markers in diagnosis of papillary thyroid carcinoma: Utility of HBME1 combined with CK19 immunostaining." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 19, Issue 12, pp. 1631-7, (2006) (PubMed).

Details zu EPS8

Target: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Andere Bezeichnung: EPS8 (EPS8 Produkte)

Synonyme: AW261790 antikoerper, MGC81285 antikoerper, MGC146320 antikoerper, zgc:56041 antikoerper, epidermal growth factor receptor pathway substrate 8 antikoerper, epidermal growth factor receptor pathway substrate 8 L homeolog antikoerper, EPS8 antikoerper, Eps8 antikoerper, eps8.L antikoerper, eps8 antikoerper

Hintergrund: Upon binding to EGF receptor, EPS8 enhances EGF-dependent mitogenic signals. It can bind multiple cellular targets. EPS8 is expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. It is expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells. EPS8 is phosphorylated by several receptor tyrosine kinases. The protein contains 1 PH domain and 1 SH3 domain.

Molekulargewicht: 91882

Gen-ID: 2059

NCBI Accession: NP_004438

UniProt: Q12929

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization