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Adenylate Kinase 5 Antikörper (N-Term)

Dieses Anti-Adenylate Kinase 5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Adenylate Kinase 5 in WB und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN392733

Kurzübersicht für Adenylate Kinase 5 Antikörper (N-Term) (ABIN392733)

Target

Alle Adenylate Kinase 5 (AK5) Antikörper anzeigen
Adenylate Kinase 5 (AK5)

Reaktivität

  • 41
  • 16
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 34
  • 7
Kaninchen

Klonalität

  • 35
  • 5
Polyklonal

Konjugat

  • 26
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Adenylate Kinase 5 Antikörper ist unkonjugiert

Applikation

  • 28
  • 21
  • 19
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB3883
  • Bindungsspezifität

    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 404-433, N-Term

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This AK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-433 amino acids from the N-terminal region of human AK5.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Saito, Kitamura, Hijikata, Tomizawa-Murasawa, Tanaka, Takagi, Uchida, Suzuki, Sone, Najima, Ozawa, Wake, Taniguchi, Shultz, Ohara, Ishikawa: "Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells." in: Science translational medicine, Vol. 2, Issue 17, pp. 17ra9, (2010) (PubMed).

  • Target

    Adenylate Kinase 5 (AK5)

    Andere Bezeichnung

    AK5

    Hintergrund

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

    Molekulargewicht

    63333

    Gen-ID

    26289

    NCBI Accession

    NP_036225, NP_777283

    UniProt

    Q9Y6K8

    Pathways

    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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