UCK Antikörper (N-Term)

Produktnummer ABIN392730

Dieses Anti-UCK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UCK in WB und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für UCK Antikörper (N-Term) (ABIN392730)

Target: UCK (Uridine-Cytidine Kinase (UCK))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB3874

Produktdetails anti-UCK Antikörper

Bindungsspezifität: AA 18-48, N-Term

Homologie: B, Pig, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This UCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-48 amino acids from the N-terminal region of human UCK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-UCK Antikörper (ABIN392730)

Zlatopolskiy, Morgenroth, Kunkel, Urusova, Dinger, Kull, Lepping, Reske: "Synthesis and biologic study of IV-14, a new ribonucleoside radiotracer for tumor visualization." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 50, Issue 11, pp. 1895-903, (2009) (PubMed).

Details zu UCK

Target: UCK (Uridine-Cytidine Kinase (UCK))

Andere Bezeichnung: UCK

Hintergrund: UCK1 (Uridine-cytidine kinase 1) phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. This enzyme does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Of note, UCK1 is able to use either ATP or GTP as a phosphate donor. UCK1 also possesses the ability to phosphorylate a number of cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.

Molekulargewicht: 22222

Gen-ID: 51727

NCBI Accession: NP_001129612, NP_057392

UniProt: P30085

Pathways: Nucleotide Phosphorylation