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TLK2 Antikörper (AA 141-171)

This anti-TLK2 antibody (ABIN392686) is a Rabbit Polyclonal antibody detecting TLK2 in WB. Suitable for Human, Mouse.
Produktnummer ABIN392686

Kurzübersicht für TLK2 Antikörper (AA 141-171) (ABIN392686)

Target

Alle TLK2 Antikörper anzeigen
TLK2 (Tousled-Like Kinase 2 (TLK2))

Reaktivität

  • 54
  • 22
  • 16
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus

Wirt

  • 51
  • 3
Kaninchen

Klonalität

  • 51
  • 3
Polyklonal

Konjugat

  • 24
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TLK2 Antikörper ist unkonjugiert

Applikation

  • 42
  • 21
  • 13
  • 13
  • 6
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

RB3046
  • Bindungsspezifität

    • 15
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 141-171

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This TLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-171 amino acids from the Central region of human TLK2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    TLK2 (Tousled-Like Kinase 2 (TLK2))

    Andere Bezeichnung

    TLK2

    Hintergrund

    TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.

    Molekulargewicht

    87661

    Gen-ID

    11011

    NCBI Accession

    NP_001106178, NP_006843

    UniProt

    Q86UE8
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