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NEK4 Antikörper (C-Term)

NEK4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB2963 unconjugated
Produktnummer ABIN392651
  • Target Alle NEK4 Antikörper anzeigen
    NEK4 (NIMA related kinase 4 (NEK4))
    Bindungsspezifität
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 793-824, C-Term
    Reaktivität
    • 51
    • 15
    • 3
    Human
    Wirt
    • 47
    • 4
    Kaninchen
    Klonalität
    • 48
    • 3
    Polyklonal
    Konjugat
    • 26
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NEK4 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 27
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NEK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 793-824 amino acids from the C-terminal region of human NEK4.
    Klon
    RB2963
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.
    Haltbarkeit
    6 months
  • Target
    NEK4 (NIMA related kinase 4 (NEK4))
    Andere Bezeichnung
    NEK4 (NEK4 Produkte)
    Synonyme
    NRK2 antikoerper, STK2 antikoerper, pp12301 antikoerper, ATNEK4 antikoerper, MAA21.6 antikoerper, NIMA-RELATED KINASE4 antikoerper, NIMA-related kinase 4 antikoerper, NIMA (never in mitosis gene a)-related expressed kinase 4 antikoerper, NIMA related kinase 4 antikoerper, NIMA-related kinase 4 antikoerper, Nek4 antikoerper, NEK4 antikoerper
    Hintergrund
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
    Molekulargewicht
    94597
    NCBI Accession
    NP_001180462, NP_003148
    UniProt
    P51957
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