BRD3 Antikörper (C-Term)

Produktnummer ABIN392610

Dieses Anti-BRD3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BRD3 in WB und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für BRD3 Antikörper (C-Term) (ABIN392610)

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB3471

Produktdetails anti-BRD3 Antikörper

Bindungsspezifität: AA 672-702, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This BRD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 672-702 amino acids from the C-terminal region of human BRD3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-BRD3 Antikörper (ABIN392610)

Klein, Kabala, Grabiec, Gay, Kolling, Lin, Gay, Tak, Prinjha, Ospelt, Reedquist: "The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts." in: Annals of the rheumatic diseases, (2014) (PubMed).

Details zu BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Andere Bezeichnung: BRD3

Hintergrund: This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.

Molekulargewicht: 79542

Gen-ID: 8019

NCBI Accession: NP_031397

UniProt: Q15059

Pathways: Chromatin Binding