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MLK4 Antikörper (N-Term)

KIAA1804 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB12543 unconjugated
Produktnummer ABIN392542
  • Target Alle MLK4 (KIAA1804) Antikörper anzeigen
    MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))
    Bindungsspezifität
    • 12
    • 9
    • 7
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-62, N-Term
    Reaktivität
    • 36
    • 16
    • 1
    Human
    Wirt
    • 50
    Kaninchen
    Klonalität
    • 50
    Polyklonal
    Konjugat
    • 16
    • 6
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MLK4 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 35
    • 32
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This MLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human MLK4.
    Klon
    RB12543
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))
    Andere Bezeichnung
    MLK4 (KIAA1804 Produkte)
    Synonyme
    MLK4 antikoerper, RP5-862P8.2 antikoerper, dJ862P8.3 antikoerper, Mlk4 antikoerper, mKIAA1804 antikoerper, mitogen-activated protein kinase kinase kinase 21 antikoerper, MAP3K21 antikoerper, Map3k21 antikoerper
    Hintergrund
    Mixed-lineage kinases (MLKs) function as mitogen-activated protein kinase kinase kinases (MAP3Ks), activating the p38 and JNK signaling cascades. Systematic mutational analyses of tyrosine kinases reveal that a minimum of 30 % of colorectal cancer contain at least one mutation in the tyrosine kinases, sampling of colorect cancer cells suggest an important role of MLK4 in this process.
    Molekulargewicht
    113957
    Gen-ID
    84451
    NCBI Accession
    NP_115811
    UniProt
    Q5TCX8
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