Dieses Anti-PIM2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PIM2 in WB, IP und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Klon
RB01288
Bindungsspezifität
AA 277-308, C-Term
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This PIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-308 amino acids from the C-terminal region of human PIM2.
Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli, its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.