MAP3K6 Antikörper (C-Term)

Produktnummer ABIN392411

Produktdetails anti-MAP3K6 Antikörper

Target: MAP3K6 (Mitogen-Activated Protein Kinase Kinase Kinase 6 (MAP3K6))

Bindungsspezifität: AA 1028-1058, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1028-1058 amino acids from the C-terminal region of human MEKK6.

Klon: RB0946

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MAP3K6 Antikörper (ABIN392411)

Han, Oh, Kang, Kim, Seo, Kim, Park, Kim: "Protein profiling in human sera for identification of potential lung cancer biomarkers using antibody microarray." in: Proteomics, Vol. 9, Issue 24, pp. 5544-52, (2009) (PubMed).

Details zu MAP3K6

Target: MAP3K6 (Mitogen-Activated Protein Kinase Kinase Kinase 6 (MAP3K6))

Andere Bezeichnung: MEKK6 (MAP3K6 Produkte)

Synonyme: ASK2 antikoerper, MAPKKK6 antikoerper, MEKK6 antikoerper, Ask2 antikoerper, mitogen-activated protein kinase kinase kinase 6 antikoerper, MAP3K6 antikoerper, Map3k6 antikoerper

Hintergrund: Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.

Molekulargewicht: 142596

Gen-ID: 9064

NCBI Accession: NP_004663

UniProt: O95382