This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human ACVRL1.
ACVRL1 antikoerper, vgb antikoerper, alk1 antikoerper, zehn1109 antikoerper, hm:zehn1109 antikoerper, ACVRLK1 antikoerper, ALK-1 antikoerper, ALK1 antikoerper, HHT antikoerper, HHT2 antikoerper, ORW2 antikoerper, SKR3 antikoerper, TSR-I antikoerper, R-3 antikoerper, R3 antikoerper, SETHKIR antikoerper, AI115505 antikoerper, AI427544 antikoerper, Acvrlk1 antikoerper, Alk1 antikoerper, activin A receptor like type 1 antikoerper, activin A receptor type II-like 1 antikoerper, activin A receptor, type II-like 1 antikoerper, ACVRL1 antikoerper, acvrl1 antikoerper, Acvrl1 antikoerper
Hintergrund
ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.