BACE1 Antikörper (AA 476-501)
Kurzübersicht für BACE1 Antikörper (AA 476-501) (ABIN392200)
Target
Alle BACE1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 476-501
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Homologie
- B, Rat
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This BACE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-501 amino acids from human BACE.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- BACE1 (Beta-secretase 1 (BACE1))
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Andere Bezeichnung
- BACE
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Hintergrund
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
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Molekulargewicht
- 55764
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Gen-ID
- 23621
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NCBI Accession
- NP_001193978, NP_036236, NP_620427, NP_620428, NP_620429
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UniProt
- P56817
Target
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