RUNX2 Antikörper (AA 445-474)

Produktnummer ABIN392133

Dieses Anti-RUNX2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RUNX2 in WB, FACS und IHC (p). Geeignet für Human.

Kurzübersicht für RUNX2 Antikörper (AA 445-474) (ABIN392133)

Target: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB15321

Produktdetails anti-RUNX2 Antikörper

Bindungsspezifität: AA 445-474

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids surrounding S465 of human RUNX2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu RUNX2

Target: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Andere Bezeichnung: RUNX2

Hintergrund: Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).

Molekulargewicht: 56648

Gen-ID: 860

NCBI Accession: NP_001015051, NP_001019801

UniProt: Q13950