TNK1 Antikörper (AA 256-286)

Produktnummer ABIN392113

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TNK1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für TNK1 Antikörper (AA 256-286) (ABIN392113)

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB3104

Produktdetails anti-TNK1 Antikörper

Bindungsspezifität: AA 256-286

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This TNK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-286 amino acids from the Central region of human TNK1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-TNK1 Antikörper (ABIN392113)

Henderson, Gonzales, Arora, Choudhary, Trent, Von Hoff, Mousses, Azorsa: "High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells." in: Molecular cancer research : MCR, Vol. 9, Issue 6, pp. 724-32, (2011) (PubMed).

Details zu TNK1

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Andere Bezeichnung: TNK1

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Molekulargewicht: 72468

Gen-ID: 8711

NCBI Accession: NP_001238831, NP_003976

UniProt: Q13470