PTK6 Antikörper (N-Term)

Produktnummer ABIN392105

Der Kaninchen Polyklonal Anti-PTK6-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, PTK6 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für PTK6 Antikörper (N-Term) (ABIN392105)

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB3073-3074

Produktdetails anti-PTK6 Antikörper

Bindungsspezifität: AA 11-41, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This BRK (PTK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human BRK (PTK6).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-PTK6 Antikörper (ABIN392105)

Xu, Ye, Wu, He, Tan, Xiao, Wu, Yu, Mai, Li, Peng, Huang, Li, Zhang, Zhu, Qin: "Overexpression of PTK6 predicts poor prognosis in bladder cancer patients." in: Journal of Cancer, Vol. 8, Issue 17, pp. 3464-3473, (2018) (PubMed).

Chen, Ma, Cao, Huang, Zeng, Wen: "Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 317, (2014) (PubMed).

Details zu PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Andere Bezeichnung: BRK (PTK6)

Hintergrund: PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation.

Molekulargewicht: 51834

Gen-ID: 5753

NCBI Accession: NP_001243287, NP_005966

UniProt: Q13882