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BLK Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-BLK-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, BLK in Proben von Human und Maus zu detektieren.
Produktnummer ABIN392087

Kurzübersicht für BLK Antikörper (N-Term) (ABIN392087)

Target

Alle BLK Antikörper anzeigen
BLK (B Lymphoid Tyrosine Kinase (BLK))

Reaktivität

  • 66
  • 23
  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 52
  • 11
  • 1
Kaninchen

Klonalität

  • 54
  • 12
Polyklonal

Konjugat

  • 39
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BLK Antikörper ist unkonjugiert

Applikation

  • 50
  • 35
  • 29
  • 13
  • 13
  • 6
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB03107
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This BLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BLK.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    BLK (B Lymphoid Tyrosine Kinase (BLK))

    Andere Bezeichnung

    BLK

    Hintergrund

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

    Molekulargewicht

    57706

    Gen-ID

    640

    NCBI Accession

    NP_001706

    UniProt

    P51451

    Pathways

    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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