PDGFRL Antikörper (C-Term)

Produktnummer ABIN392037

Produktdetails anti-PDGFRL Antikörper

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Bindungsspezifität: AA 328-357, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFRL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-357 amino acids from the C-terminal region of human PDGFRL.

Klon: RB2001

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Andere Bezeichnung: PDGFRL (PDGFRL Produkte)

Synonyme: zgc:56104 antikoerper, zgc:77677 antikoerper, MGC82397 antikoerper, PDGFRL antikoerper, pdgrl antikoerper, prlts antikoerper, MGC107901 antikoerper, PDGRL antikoerper, PRLTS antikoerper, 1110039P19Rik antikoerper, AV013190 antikoerper, platelet-derived growth factor receptor-like antikoerper, platelet derived growth factor receptor like L homeolog antikoerper, platelet derived growth factor receptor like antikoerper, pdgfrl antikoerper, pdgfrl.L antikoerper, PDGFRL antikoerper, Pdgfrl antikoerper

Hintergrund: PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.

Molekulargewicht: 41861

Gen-ID: 5157

NCBI Accession: NP_006198

UniProt: Q15198

Pathways: Platelet-derived growth Factor Receptor Signaling