CA3 Antikörper (N-Term)

Produktnummer ABIN391954

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CA3 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für CA3 Antikörper (N-Term) (ABIN391954)

Target: CA3 (Carbonic Anhydrase III (CA3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB18370

Produktdetails anti-CA3 Antikörper

Bindungsspezifität: AA 17-46, N-Term

Homologie: Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human CA3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CA3 Antikörper (ABIN391954)

Pollard, Shephard, Freed, Liddell, Chakrabarti: "Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration." in: Aging, Vol. 8, Issue 10, pp. 2425-2436, (2017) (PubMed).

Araujo, Vaz, Fujimura, Fonseca, de Lima, Canhão, Venturini, Cardozo, Carvalho, Napimoga, Goulart, Gonçalves, Ueira-Vieira: "Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of carbonic anhydrase III selected in a murine model by phage display." in: Arthritis research & therapy, Vol. 17, pp. 168, (2016) (PubMed).

Details zu CA3

Target: CA3 (Carbonic Anhydrase III (CA3))

Andere Bezeichnung: CA3

Hintergrund: Carbonic anhydrase III (CAIII) is a member of carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.

Molekulargewicht: 29557

Gen-ID: 761

NCBI Accession: NP_005172

UniProt: P07451