Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Cullin 5 Antikörper (C-Term)

CUL5 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB17926 unconjugated
Produktnummer ABIN391834
  • Target Alle Cullin 5 (CUL5) Antikörper anzeigen
    Cullin 5 (CUL5)
    Bindungsspezifität
    • 15
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 747-774, C-Term
    Reaktivität
    • 45
    • 21
    • 18
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 44
    • 1
    Kaninchen
    Klonalität
    • 45
    Polyklonal
    Konjugat
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cullin 5 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 13
    • 13
    • 13
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    Rb
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CUL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 747-774 amino acids from the C-terminal region of human CUL5.
    Klon
    RB17926
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Cullin 5 (CUL5)
    Andere Bezeichnung
    CUL5 (CUL5 Produkte)
    Synonyme
    cul5 antikoerper, wu:fd17d09 antikoerper, wu:fi20h12 antikoerper, xx:11fd17d09 antikoerper, zgc:66185 antikoerper, Xcullin5 antikoerper, CG1401 antikoerper, CUL5 antikoerper, Cul5 antikoerper, Cullin 5 antikoerper, Cullin5 antikoerper, Dmel\\CG1401 antikoerper, cul-5 antikoerper, vacm-1 antikoerper, vacm1 antikoerper, VACM-1 antikoerper, VACM1 antikoerper, 4921514I20Rik antikoerper, 8430423K24Rik antikoerper, AI852817 antikoerper, C030032G03Rik antikoerper, C330021I08Rik antikoerper, Cullin-5 antikoerper, cullin 5a antikoerper, cullin 5 L homeolog antikoerper, Cullin 5 antikoerper, cullin 5 antikoerper, Cullin-5 antikoerper, cul5a antikoerper, cul5.L antikoerper, Cul5 antikoerper, CUL5 antikoerper, cul5 antikoerper, cul-5 antikoerper
    Hintergrund
    CUL5 is a core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. It seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein and may form a cell surface vasopressin receptor.
    Molekulargewicht
    90955
    Gen-ID
    8065
    NCBI Accession
    NP_003469
    UniProt
    Q93034
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Sie sind hier:
Kundenservice