CDK10 Antikörper (N-Term)

Produktnummer ABIN391741

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CDK10 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für CDK10 Antikörper (N-Term) (ABIN391741)

Target: CDK10 (Cyclin-Dependent Kinase 10 (CDK10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB3172

Produktdetails anti-CDK10 Antikörper

Bindungsspezifität: AA 1-32, N-Term

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CDK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human CDK10.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CDK10 Antikörper (ABIN391741)

Hong, Zhang, You, Qiu, Giuliano, Cui, Zhang, Cui: "Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study." in: BMC cancer, Vol. 15, pp. 548, (2015) (PubMed).

You, Li, Qin, Zhang, Song, Ran, Gao: "Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report." in: Cellular oncology (Dordrecht), Vol. 38, Issue 6, pp. 485-91, (2015) (PubMed).

Leman, Magheli, Yong, Netto, Hinz, Getzenberg: "Identification of nuclear structural protein alterations associated with seminomas." in: Journal of cellular biochemistry, Vol. 108, Issue 6, pp. 1274-9, (2009) (PubMed).

Iorns, Turner, Elliott, Syed, Garrone, Gasco, Tutt, Crook, Lord, Ashworth: "Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer." in: Cancer cell, Vol. 13, Issue 2, pp. 91-104, (2008) (PubMed).

Details zu CDK10

Target: CDK10 (Cyclin-Dependent Kinase 10 (CDK10))

Andere Bezeichnung: CDK10

Hintergrund: CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase.

Molekulargewicht: 41038

Gen-ID: 8558

NCBI Accession: NP_001092003, NP_001153839, NP_443713, NP_443714

UniProt: Q15131