Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-ADAM9 Antikörper wird verwendet zum Nachweis von ADAM9 in Proben von Human und Maus. Er wurde validiert für WB und FACS.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ADAM9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from the N-terminal region of human ADAM9.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Chen, Chang: "Arecoline-induced death of human leukemia K562 cells is associated with surface up-modulation of TNFR2." in: Journal of cellular physiology, Vol. 227, Issue 5, pp. 2240-51, (2012) (PubMed).
Liu, Chang: "Suppression of ADAM17-mediated Lyn/Akt pathways induces apoptosis of human leukemia U937 cells: Bungarus multicinctus protease inhibitor-like protein-1 uncovers the cytotoxic mechanism." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30506-15, (2010) (PubMed).
Target
ADAM9
(ADAM Metallopeptidase Domain 9 (ADAM9))
Andere Bezeichnung
ADAM9
Hintergrund
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.