GUCY1A1 Antikörper (N-Term)

Produktnummer ABIN391201

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GUCY1A1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für GUCY1A1 Antikörper (N-Term) (ABIN391201)

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GUCY1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB07757

Produktdetails anti-GUCY1A1 Antikörper

Bindungsspezifität: AA 269-300, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-GUCY1A1 Antikörper (ABIN391201)

Hedlund, Karlsson, Osborn, Ludwig, Isacson: "Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection." in: Brain : a journal of neurology, Vol. 133, Issue Pt 8, pp. 2313-30, (2010) (PubMed).

Details zu GUCY1A1

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Andere Bezeichnung: Guanylyl Cyclase alpha 1 (GUCY1A3)

Hintergrund: Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.

Molekulargewicht: 77452

Gen-ID: 2982

NCBI Accession: NP_000847, NP_001124154, NP_001124155, NP_001124156, NP_001124159, NP_001243378

UniProt: Q02108

Pathways: Myometrial Relaxation and Contraction