DTYMK Antikörper (C-Term)

Produktnummer ABIN391075

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DTYMK in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für DTYMK Antikörper (C-Term) (ABIN391075)

Target: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DTYMK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB5576

Produktdetails anti-DTYMK Antikörper

Bindungsspezifität: AA 164-194, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DTYMK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-194 amino acids from the C-terminal region of human DTYMK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu DTYMK

Target: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Andere Bezeichnung: DTYMK

Hintergrund: Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Molekulargewicht: 23819

Gen-ID: 1841

NCBI Accession: NP_036277

UniProt: P23919

Pathways: Nucleotide Phosphorylation