ALS2 Antikörper (C-Term)
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- Target Alle ALS2 Antikörper anzeigen
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
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Bindungsspezifität
- AA 1248-1277, C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ALS2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Rat
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This ALS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2.
- Klon
- RB18853
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ALS2 Primärantikörper
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:50~100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
- Andere Bezeichnung
- ALS2 (ALS2 Produkte)
- Hintergrund
- ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.
- Molekulargewicht
- 183634
- Gen-ID
- 57679
- NCBI Accession
- NP_001129217, NP_065970
- UniProt
- Q96Q42
- Pathways
- Skeletal Muscle Fiber Development
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