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Parkin Antikörper (N-Term)

Dieses Anti-Parkin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Parkin in WB. Geeignet für Drosophila melanogaster.
Produktnummer ABIN390387

Kurzübersicht für Parkin Antikörper (N-Term) (ABIN390387)

Target

Parkin (PARK)

Reaktivität

Drosophila melanogaster

Wirt

  • 1
Kaninchen

Klonalität

  • 1
Polyklonal

Konjugat

  • 1
Dieser Parkin Antikörper ist unkonjugiert

Applikation

  • 1
  • 1
Western Blotting (WB)

Klon

RB8213
  • Bindungsspezifität

    AA 82-111, N-Term

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This Drosophila Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the N-terminal region of human Drosophila Parkin.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    Parkin (PARK)

    Andere Bezeichnung

    Drosophila Parkin

    Hintergrund

    Parkin is thought to play a role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. Mutations in the human version of the protein are known to cause autosomal recessive juvenile parkinsonism.

    Molekulargewicht

    54105

    Gen-ID

    40336

    UniProt

    Q7KTX7
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