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c-Rel Antikörper (C-Term)

This anti-c-Rel antibody (ABIN390316) is a Rabbit Polyclonal antibody detecting c-Rel in WB. Suitable for Human, Mouse.
Produktnummer ABIN390316

Kurzübersicht für c-Rel Antikörper (C-Term) (ABIN390316)

Target

Alle c-Rel Antikörper anzeigen
c-Rel (REL proto-oncogene (c-Rel))

Reaktivität

  • 81
  • 22
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Human, Maus

Wirt

  • 74
  • 10
  • 1
Kaninchen

Klonalität

  • 67
  • 18
Polyklonal

Konjugat

  • 39
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser c-Rel Antikörper ist unkonjugiert

Applikation

  • 57
  • 33
  • 13
  • 13
  • 11
  • 8
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB)

Klon

RB8325
  • Bindungsspezifität

    • 23
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 586-619, C-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This C-rel (NFkB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-619 amino acids from the C-terminal region of human C-rel (NFkB).

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    c-Rel (REL proto-oncogene (c-Rel))

    Andere Bezeichnung

    C-rel (NFkB)

    Hintergrund

    Nuclear factor (NF)-kappa B is a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NF-kB regulates the expression of a wide variety of genes that involved in apoptosis, viral life cycle, tumorigenesis, autoimmune diseases and inflammation. NF-kB is a heterodimer of members of the rel family of proteins such as p50, p65, and c-rel. In most cells, inhibitory IkB proteins sequester NF-kB/Rel in the cytoplasm. Cellular stimulation precipitates degradation of IkB and modification of NF-kB/Rel proteins, permitting translocation of NF-kB/Rel (c-Rel and RelA) to the nucleus for action on target genes. The important role of c-Rel in B-cell development, growth, and survival has been intensively studied, as well as its function in differentiation and lymphopoiesis (particularly lymphoid cancer).

    Molekulargewicht

    68520

    Gen-ID

    5966

    NCBI Accession

    NP_002899

    UniProt

    Q04864
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